Dermatica - Smiling woman

Reduce pigmentation with prescription skincare

Start seeing results within 12 weeks with active ingredients you won’t find in any hyperpigmentation cream on the high street.

Start your free trial

Just pay a $4.99 prescribing fee.

Dark spots? Here's why it happens

Dark Spots and age spots
Freckles
Melasma
Post acne pigmentation

Dark spots? Here's why it happens

What is Hyperpigmentation?

Skin can sometimes produce a higher amount of melanin, which is the natural pigment in your skin. This can be due to a range of skin conditions and lead to darker spots or patches on your skin's surface.

Results you’ll love -
here’s the proof

Start your free trial

Just pay a $4.99 prescribing fee.

Evidence-backed active ingredients

To fade hyperpigmentation for good, we'll get you there with the right combination for your exact skin.

The SmartBase

Your personalized formula is supercharged with powerful prescription ingredients and blended with our hydrating SmartBase cream, which contains hyaluronic acid, ceramides, glycerin and panthenol for best results.

Locks in moisture and softens illustration

Locks in moisture and softens

Nourishes your epidermis on multiple levels illustration

Nourishes your epidermis on multiple levels

Strengthens your skin barrier illustration

Strengthens your skin barrier

Woman applying SmartBase
capsules with blue and white halves stacked in a zigzag pattern against a grey background

Upgrade your routine with oral antibiotics

Oral antibiotics, combined with a personalized formula, can help you target multiple symptoms at once — speeding up relief and promoting better results from your topical treatment.*

Interested in adding to your plan? Eligible customers can request an evaluation via the dashboard for our dermatology team's assessment.

$59.99 | 16 week course
*Doxycycline is available subject to clinical review of individual skin concerns and eligibility. Image for illustrative purposes only.

Switch to prescription skincare in 3 easy steps

  1. reaching goal illustration

    Step 01

    Complete an online consultation

    This will help our dermatology experts prescribe the right formula for your skin

  2. designing treatment plan illustration

    Step 02

    Apply your formula once a night

    With the perfect combination of active ingredients for your unique skin.

  3. adapting treatment formula illustration

    Step 03

    Check in throughout your journey

    We’ll monitor your progress and adjust your treatment as needed.

Start your free trial

Just pay a $4.99 prescribing fee.

Dermatology, designed for you

Dermatology designed for you
  • A personalized formula, developed by experts

    You’ll get a personalized, evidence-based prescription treatment, tailored to your treatment goals.

  • Delivered to you every 56 days (approx.)

    Your bespoke plan arrives with #{ treatments_per_order_word } bottles every 56 days (approximately), and adapts to your skin’s progress.

  • 24/7 support

    You’ll have free, unlimited access to dermatology experts, whenever you need.

  • You’re in total control

    You can pause, reschedule or cancel your plan online. No strings attached.

First month $4.99

then $29.95/month

Support your treatment with our routine essentials

Our range of daily essentials were designed by dermatologists to work alongside active ingredients. Fragrance free, gentle and effective for all skin types.

Read what others say, in their own words

Showing our favorite reviews
“I love the personalized service & for a great price. I have been really impressed with the product - my skin looks great. It was easy to do the consultation & the retinol cream has been a pleasure to use. It started on a lower % of 0.25 & is now 0.5. Fantastic.”
Sara Caistor
Verified Facebook review
“Amazing service. Brilliant product that I used to pay hundreds of pounds for and amazing results. Tailored to my own skin problems and I can’t recommend Dermatica enough. Easy to cancel if you’re not happy but I guarantee you will be so pleased with the results you will carry on just as I have 😊😊”
Claire Smith
Verified Google review
“Having tried many products before to help with my skin I can honestly say that I have been very impressed with Dermatica...my skin is probably the best it has been in years. Getting the formula was simple enough and the results speak for themselves. Worth every penny.”
Erin Beale
Verified Facebook review
“My skin has been the best it's ever been since I was a teenager my pigmentation has significantly cleared and acne has been kept at bay. I will never use anything other than dermatica I am so relieved I found this brand and have recommended to others. I receive compliments on how good my skin looks it's taken years off me.”
Maria
Verified Reviews.io review
“I am such a fan of Dermatica and their service. Very easy to manage your subscription but as someone with incredibly problematic skin (who last week got complimented by a stranger on it!) I wouldn't be without it. I truly believe prescription skincare offers so much more than all the creams and lotions you can buy OTC.”
TheOGCCL
Verified Mumsnet review
“I’ve been using Tretinoin for almost three months now, and I’m loving it. Great customer service, great results and I’m now up to my maximum dose. I’m definitely seeing some peeling, but nothing that wasn’t explained in the literature you receive with the product. It’s saved me an absolute fortune on skincare, as I used to buy every new product on the market that promised the earth and delivered nothing.”
Sarah Blackley
Verified Facebook review
“The initial process of having the assessment and getting my personalized formula was so fast. Shortly after I received my products which I love so much and it has only been 2 weeks. My major skin concern was uneven dull skin tone, enlarged pores and fine lines. My skin is so glowing like it has never been before! It just looks so healthy and feels so soft. I had a few acne marks which are now faded.”
Réka Bódi
Verified Facebook review
“Dermatica has completely revolutionised my skin care. I am now 63 but my skin has never looked so good or been so healthy. My monthly delivery has become a part of my life now and I will continue for as long as I am able. The service is also second to none. Any questions I've submitted have always been answered promptly and without fuss. I would highly recommend Dermatica to anyone who cares about looking their best for as long as possible.”
Catherine
Verified Reviews.io review
“I have PCOS and have struggled with acne for over 10 years, and have tried what feels like every acne medication available. My skin has never been better than while using my personalized Dermatica treatment, and I'm so happy! The subscription service is also very convenient, so I never have to worry about running out or having to go to the pharmacy for it.”
Bella Duncan
Verified Facebook review
“Love Dermatica. My skin is bright and the large pores and blackheads on my nose have gone. I've been using it for 6 months with Dermatica controlling the strength of the creams supplied to suit. I must say it has saved me a fortune on buying stuff to try and it not working and I can now use basic cleanser and moisturiser.”
Blossomgate22
Verified Mumsnet review
Dr Catriona Maybury, Consultant Dermatologist
“Hyperpigmentation following sun exposure, or associated with an inflammatory skin condition like acne, can be difficult to treat. Our formulas are tailored to address the cause and improve pigmentation”
Dr Catriona Maybury, Consultant Dermatologist
Start your free trial

Just pay a $4.99 prescribing fee.

Hyperpigmentation FAQs

What to expect from treatment
When you first start using a topical treatment, you may notice your skin becoming flaky and slightly swollen. The treatments can also make your skin feel dry and tight as well as give you a burning, itching or stinging sensation. If you experience the above reaction, please do not worry, this is a normal response when starting treatment. To allow your skin to get used to your treatment, we recommend sticking to a simple skincare routine and applying a small amount at first to build up your tolerance. It's also OK to take rest days from treatment in between, before building up gradually to daily use. Applying a small amount of moisturizer to the skin before applying treatment, and after, can also help reduce side effects while still delivering the same great results.
What if I have acne and hyperpigmentation?
We recommend treating the acne first. Often, hyperpigmentation is caused by the dark spots that acne leaves behind, also known as post-inflammatory hyperpigmentation. Until the cause of the hyperpigmentation is addressed, the dark marks will continue to occur. The good news is, many of the products used in the treatment of acne also treat hyperpigmentation, so your formula will likely be treating both conditions at the same time.

Get industry-leading advice from skin experts