Personalized formulas
All treatments Acne Acne scars & pigmentation Aging Hyperpigmentation Melasma Skin glow Rosacea
Routine essentials
All Products Retinal 0.05%—0.2% Serum NEW Clarifying Azelaic Acid 15–20% Cream The Balancing Kit SAVE The Nourishing Kit SAVE Balancing Glycerin Gel Cleanser Caring Squalane Cream Cleanser Hydrating Hyaluronic Acid + Vit B5 Serum Soothing Centella Gel Moisturizer Nourishing Ceramide + Peptide Moisturizer Restoring Ceramide Skin Balm Blemish Control Kit Brightening & Barrier Repair Kit Advanced Dark Spot Corrector Serum Daily Hydration 5HA+Cica Serum
Dermatica products
Your skincare, solved
Your skincare should be anything but routine, and these derm-approved products are developed to achieve your skin’s incredible potential.
View Retinal 0.05% Serum Page
A clinically backed anti-aging serum with retinal, designed with dermatologists to target and help prevent advanced signs of skin aging.
View Clarifying Azelaic Acid 15–20% Cream Page
Fade the appearance of dark spots for a brighter, more even skin tone with this multi-tasking cream.
View The Balancing Kit Page
Your complete starter kit for blemish and breakout-prone skin.
View The Nourishing Kit Page
Your complete starter kit for glowing, healthy skin.
View Balancing Glycerin Gel Cleanser Page
Rebalance oily, blemish-prone skin with a gentle makeup-removing cleanser.
View Caring Squalane Cream Cleanser Page
Nourish balanced or dry skin with a makeup-removing, cream-to-oil-to-milk cleanser.
View Hydrating Hyaluronic Acid + Vit B5 Serum Page
Give dry, oily or combination skin a hydrating boost with moisture-locking vitamin B5 and smoothing hyaluronic acid.
View Soothing Centella Gel Moisturizer Page
Protect and hydrate oily and combination skin with this lightweight oil-free gel moisturizer.
View Nourishing Ceramide + Peptide Moisturizer Page
Effective hydration for balanced or dry skin with moisture-locking niacinamide and soothing ceramides.
View Restoring Ceramide Skin Balm Page
Speed up retinization recovery with a targeted barrier balm for dry, irritated or flaky skin.
View Blemish Control Kit Page
Your daily routine for blemish-prone skin.
View Brightening & Barrier Repair Kit Page
Your radiance-boosting daily routine for glowing, resilient skin.
View Advanced Dark Spot Corrector Serum Page
A precision dark spot serum, combining 3 science-backed actives with encapsulation technology for visibly clear, radiant skin.
View Daily Hydration 5HA+Cica Serum Page
An ultra-light, hydrating serum with five molecular weights of hyaluronic acid to support skin barrier health and resilience.
acne
Prescription treatments made for you
Breakouts. Pigmentation. Wrinkles - we have you covered. The best ingredients for healthy skin tailored to yours needs.
acne
Prescription acne treatments
Treat and clear spots, pimples, whiteheads, blackheads, breakouts, blemishes and cystic acne.
acne-scars
Prescription treatments for acne scars & pigmentation
Reduce red or dark marks from acne, and smooth the skin’s texture.
anti-ageing
Prescription anti-aging treatments
Reduce wrinkles, improve pigmentation, skin texture and smoothness.
hyperpigmentation
Prescription hyperpigmentation treatments
Reduce the appearance of wrinkles, scars marks, dark spots and hyper-pigmentation.
melasma
Prescription melasma treatments
Reduce pigmentation from melasma to improve and even out your skin tone.
vitality
Prescription skin glow treatments
Achieve healthy-looking and radiant skin.
rosacea
Prescription rosacea treatments
Reduce and control redness or flare-ups and protect sensitive skin.
Adapalene Benzoyl peroxide Tretinoin
Other ingredients
Clindamycin, hydroquinone, ivermectin, metronidazole, niacinamide
ingredients
Evidence-based ingredients
Our formulas are made with effective science-backed actives that are gentle on your skin.
How it works Pricing Meet the team Support centre Our mission Read our blog Affiliates
Dermatica - Smiling woman

Reduce pigmentation with prescription skincare

Start seeing results within 12 weeks with active ingredients you won’t find in any hyperpigmentation cream on the high street.

Start your free trial

Save over 85% on your first month

Dark spots? Here's why it happens

Dark Spots and age spots
Freckles
Melasma
Post acne pigmentation

Dark spots? Here's why it happens

What is Hyperpigmentation?

Skin can sometimes produce a higher amount of melanin, which is the natural pigment in your skin. This can be due to a range of skin conditions and lead to darker spots or patches on your skin's surface.

Results you’ll love -
here’s the proof

Start your free trial

Save over 85% on your first month

Dermatica - Check In With Your Dermatology Team Screen View

What’s included?

  1. Powerful personalized formula
  2. Evidence-based ingredients
  3. Up to 20x stronger than the high street
  4. Dashboard to track your progress
  5. Unlimited treatment adjustments
Start your free trial
Discount Tag Illustration Save over 85% on your first month

Evidence-backed active ingredients

To fade hyperpigmentation for good, we'll get you there with the right combination for your exact skin.

View all ingredients

The SmartBase

Your personalized formula is supercharged with powerful prescription ingredients and blended with our hydrating SmartBase cream, which contains hyaluronic acid, ceramides, glycerin and panthenol for best results.

Explore our ingredients
Locks in moisture and softens illustration

Locks in moisture and softens

Nourishes your epidermis on multiple levels illustration

Nourishes your epidermis on multiple levels

Strengthens your skin barrier illustration

Strengthens your skin barrier

Woman applying SmartBase
capsules with blue and white halves stacked in a zigzag pattern against a grey background

Could oral antibiotics be right for you?

Oral antibiotics, combined with a personalized formula, can help you target multiple symptoms at once — speeding up relief and promoting better results from your topical treatment.*

Interested in adding to your plan? Eligible customers can request an evaluation via the dashboard for our dermatology team's assessment.

Log in
*Doxycycline is available subject to clinical review of individual skin concerns and eligibility. Image for illustrative purposes only.

How it works

  1. reaching goal illustration

    Step 01

    Complete an online consultation

    This will help our dermatology experts prescribe the right formula for your skin

  2. designing treatment plan illustration

    Step 02

    Apply your formula once a night

    With the perfect combination of active ingredients for your unique skin.

  3. adapting treatment formula illustration

    Step 03

    Check in throughout your journey

    We'll monitor your progress and adjust your treatment as needed.

Start your free trial

Save over 85% on your first month

Dermatology, designed for you

Dermatology designed for you
  • A personalized formula, developed by experts

    You’ll get a personalized, evidence-based prescription treatment, tailored to your treatment goals.

  • Delivered to you every 56 days (approx.)

    Your bespoke plan arrives with two bottles every 56 days (approximately), and adapts to your skin’s progress.

  • 24/7 support

    You’ll have free, unlimited access to dermatology experts, whenever you need.

  • You’re in total control

    You can pause, reschedule or cancel your plan online. No strings attached.

Save over 85% on your first month
Start your free trial

Support your treatment with our routine essentials

Our range of daily essentials were designed by dermatologists to work alongside active ingredients. Fragrance free, gentle and effective for all skin types.

Read what others say, in their own words

Showing our favorite reviews
“I love the personalized service & for a great price. I have been really impressed with the product - my skin looks great. It was easy to do the consultation & the retinol cream has been a pleasure to use. It started on a lower % of 0.25 & is now 0.5. Fantastic.”
Sara Caistor
Verified Facebook review ↗
“Amazing service. Brilliant product that I used to pay hundreds of pounds for and amazing results. Tailored to my own skin problems and I can’t recommend Dermatica enough. Easy to cancel if you’re not happy but I guarantee you will be so pleased with the results you will carry on just as I have 😊😊”
Claire Smith
Verified Google review ↗
“Having tried many products before to help with my skin I can honestly say that I have been very impressed with Dermatica...my skin is probably the best it has been in years. Getting the formula was simple enough and the results speak for themselves. Worth every penny.”
Erin Beale
Verified Facebook review ↗
“My skin has been the best it's ever been since I was a teenager my pigmentation has significantly cleared and acne has been kept at bay. I will never use anything other than dermatica I am so relieved I found this brand and have recommended to others. I receive compliments on how good my skin looks it's taken years off me.”
Maria
Verified Reviews.io review ↗
“I am such a fan of Dermatica and their service. Very easy to manage your subscription but as someone with incredibly problematic skin (who last week got complimented by a stranger on it!) I wouldn't be without it. I truly believe prescription skincare offers so much more than all the creams and lotions you can buy OTC.”
TheOGCCL
Verified Mumsnet review ↗
“I’ve been using Tretinoin for almost three months now, and I’m loving it. Great customer service, great results and I’m now up to my maximum dose. I’m definitely seeing some peeling, but nothing that wasn’t explained in the literature you receive with the product. It’s saved me an absolute fortune on skincare, as I used to buy every new product on the market that promised the earth and delivered nothing.”
Sarah Blackley
Verified Facebook review ↗
“The initial process of having the assessment and getting my personalized formula was so fast. Shortly after I received my products which I love so much and it has only been 2 weeks. My major skin concern was uneven dull skin tone, enlarged pores and fine lines. My skin is so glowing like it has never been before! It just looks so healthy and feels so soft. I had a few acne marks which are now faded.”
Réka Bódi
Verified Facebook review ↗
“Dermatica has completely revolutionised my skin care. I am now 63 but my skin has never looked so good or been so healthy. My monthly delivery has become a part of my life now and I will continue for as long as I am able. The service is also second to none. Any questions I've submitted have always been answered promptly and without fuss. I would highly recommend Dermatica to anyone who cares about looking their best for as long as possible.”
Catherine
Verified Reviews.io review ↗
“I have PCOS and have struggled with acne for over 10 years, and have tried what feels like every acne medication available. My skin has never been better than while using my personalized Dermatica treatment, and I'm so happy! The subscription service is also very convenient, so I never have to worry about running out or having to go to the pharmacy for it.”
Bella Duncan
Verified Facebook review ↗
“Love Dermatica. My skin is bright and the large pores and blackheads on my nose have gone. I've been using it for 6 months with Dermatica controlling the strength of the creams supplied to suit. I must say it has saved me a fortune on buying stuff to try and it not working and I can now use basic cleanser and moisturiser.”
Blossomgate22
Verified Mumsnet review ↗
Read more reviews
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4.7/5  |  317 reviews
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4.9/5  |  784 reviews
Dr Catriona Maybury, Consultant Dermatologist
"“Hyperpigmentation following sun exposure, or associated with an inflammatory skin condition like acne, can be difficult to treat. Our formulas are tailored to address the cause and improve pigmentation”"
Dr Catriona Maybury, Consultant Dermatologist
Start your free trial

Save over 85% on your first month

Hyperpigmentation FAQs

What to expect from treatment
When you first start using a topical treatment, you may notice your skin becoming flaky and slightly swollen. The treatments can also make your skin feel dry and tight as well as give you a burning, itching or stinging sensation. If you experience the above reaction, please do not worry, this is a normal response when starting treatment. To allow your skin to get used to your treatment, we recommend sticking to a simple skincare routine and applying a small amount at first to build up your tolerance. It's also OK to take rest days from treatment in between, before building up gradually to daily use. Applying a small amount of moisturizer to the skin before applying treatment, and after, can also help reduce side effects while still delivering the same great results.
What if I have acne and hyperpigmentation?
We recommend treating the acne first. Often, hyperpigmentation is caused by the dark spots that acne leaves behind, also known as post-inflammatory hyperpigmentation. Until the cause of the hyperpigmentation is addressed, the dark marks will continue to occur. The good news is, many of the products used in the treatment of acne also treat hyperpigmentation, so your formula will likely be treating both conditions at the same time.

Get industry-leading advice from skin experts

Skin purges
Dermatica 101

Retinoids: Why Skin Purges And How Long It Lasts

Read article
The expert
Ask our Derm

Ask A Derm: Pigmentation Problems

Read article
Melanie; before and after
Skin Journeys

Hyperpigmentation Skin Journey: Melanie, 60, Wales

Read article
hyperpigmentation
A Spotlight On

Everything You Need To Know About Hyperpigmentation

Read article
skincare products
Dermatica 101

How To Layer Your Skincare Products

Read article
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